VETORYL Capsules contain the active ingredient trilostane. Trilostane blocks the excessive production of cortisol by reversibly inhibiting the action of the enzyme 3-ß hydroxysteroid dehydrogenase. While treatment with trilostane significantly reduces serum cortisol concentrations, it has not been found to reduce aldosterone significantly.†

Starting dose

VETORYL Capsules should be administered orally once daily in the morning with food. Administration with food will significantly increase the rate and extent of absorption of VETORYL.

Ideally, the starting dose to aim for is 1.0 to 3.0 mg/lb (2.2 to 6.7 mg/kg) once a day based on body weight and capsule size. When calculating dosage, it is suggested to round down. Start at the low end of this range. If you have any questions on dosing, contact Dechra Technical Support at 866-933-2472 or support@dechra.com.

ONCE TREATMENT HAS STARTED, THE OWNER SHOULD BE ADVISED TO MONITOR THE DOG’S ACTIVITY, APPETITE AND WATER INTAKE. IF THE DOG SHOWS ANY SIGNS OF ILLNESS, ADVISE THE OWNER TO STOP TREATMENT AND CONTACT HIS OR HER VETERINARIAN IMMEDIATELY.

This information is more thoroughly explained in the dog owner information sheet, included in each carton of VETORYL Capsules.