Cushing's syndrome Treatment Options
Treatment of hyperadrenocorticism (HAC) may be achieved by surgery (adrenalectomy or trans-sphenoidal hypophysectomy), pituitary irradiation, or medical treatment. Surgery and radiotherapy are complicated procedures available only at a few specialty centers, therefore medical treatment is often the most practical and approachable treatment choice. VETORYL® Capsules (trilostane) are the only FDA approved treatment available for both pituitary-dependent hyperadrenocorticism (PDH) and adrenal-dependent hyperadrenocorticism (ADH) in the United States. Although the daily administration of VETORYL Capsules does not offer a medical cure for Cushing’s syndrome, it may allow the disease to be managed successfully, enhancing the dog’s vitality and quality of life.
A Few Facts about VETORYL Capsules:
Important VETORYL Capsules dosage and administration information
VETORYL Capsules give you the power to treat Pituitary Dependent Hyperadrenocorticism and Adrenal Dependent Hyperadrenocorticism in dogs. VETORYL Capsules have been approved by the FDA and are manufactured under current Good Manufacturing Practices (cGMP), assuring the quality and consistency of content and bioavailability, as established through the application process.
Some of the common dermatological complications of HAC may benefit from additional supportive measures. Dechra offers a complete line of products to support the restoration of a healthy skin and coat. Please visit our Dermatology page to learn more about these products.
As with all drugs, side effects may occur. In field studies and post-approval experience, the most common side effects reported were: anorexia, lethargy/depression, vomiting, diarrhea, elevated liver enzymes, elevated potassium with or without elevated sodium, elevated BUN, decreased Na/K ratio, hypoadrenocorticism, weakness, elevated creatinine, shaking, and renal insufficiency. In some cases, death has been reported as an outcome of these adverse events. VETORYL Capsules are not for use in dogs with primary hepatic or renal disease, or in pregnant dogs. Refer to the prescribing information for complete details.
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